A Short History of the Drug Receptor Concept
Book Details
Format
Hardback or Cased Book
ISBN-10
0230554156
ISBN-13
9780230554153
Publisher
Palgrave Macmillan
Imprint
Palgrave Macmillan
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Jun 25th, 2009
Print length
239 Pages
Weight
416 grams
Dimensions
22.50 x 14.60 x 2.00 cms
Product Classification:
Social & cultural historyHistory of medicineNursingSocial and cultural historyHistory of science
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The concept of specific receptors for drugs, hormones and transmitters lies at the very heart of biomedicine. This book is the first to consider the idea from its 19th century origins in the work of John Newport Langley and Paul Ehrlich, to its development of during the 20th century and its current impact on drug discovery in the 21st century.
Introduction Paul Ehrlich and his Receptor Concept The Development of the Concept of Drug Receptors in the Physiological Research of J. N. Langley The Receptors and Scientific Pharmacology I: The Critics of the Receptor Idea and Alternative Theories of Drug Action, c. 1905-1935 The Receptors and Scientific Pharmacology II: The Critics of the Receptor Idea and Alternative Research Strands: The Transmitter Theory, c. 1905-1935 Quantitative Arguments for the Existence of Drug Receptors and the Development of the Receptor Occupancy Theory, c. 1910-1960 The Dual Adrenaline Receptor Theory of Raymond P. Ahlquist (1914-1983) and its Application in Drug Development between 1950 and 1970 The Emergence of Molecular Pharmacology Conclusions Archival Sources Bibliography
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