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Advances in Medicinal Chemistry
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Advances in Medicinal Chemistry

Book Details

Format Hardback or Cased Book
ISBN-10 0762305932
ISBN-13 9780762305933
Publisher Elsevier Science & Technology
Imprint JAI Press Inc.
Country of Manufacture US
Country of Publication GB
Publication Date Dec 27th, 1999
Print length 200 Pages
Weight 512 grams
Ksh 13,150.00
Manufactured on Demand 0 in stock

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Contains four detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry and pharmacology. This work includes a comprehensive survey of the immunophilin area focussing on neuroregenerative applications in the central nervous system.
Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.

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