Anti-AIDS Drug Development
Book Details
Format
Hardback or Cased Book
ISBN-10
3718656981
ISBN-13
9783718656981
Publisher
Harwood-Academic Publishers
Imprint
Harwood-Academic Publishers
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Mar 1st, 1995
Print length
304 Pages
Weight
900 grams
Product Classification:
HIV / AIDSPharmacology
Ksh 41,400.00
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This book covers the major arenas of drug development, providing understanding of the pros and cons of the various efforts of chemists and biologists to explore newer antiviral targets for HIV replication and to look for and design molecules that will have minimal toxicities.
Curative anti-AIDS drug therapy still remains as an unconquered hurdle to drug research. This book covers significant aspects that are involved in the search, design and development of potential anti-AIDS agents with emphasis on areas related to drug development. These include enzyme inhibitors (reverse transcriptase, protease, glucosidase), inhibitors of gene expression (oligonucleotides), viral-binding inhibitors (anionic compounds and CD4 mimetics) and various plant derived products. A focus of this book is the medicinal chemistry of these classes of compounds. In addition, other areas that are pertinent to drug development are also addressed. These include HIV regulatory proteins, the development of anti-HIV-1 assays and resistance to anti-HIV-1 agents.
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