Assessment of the Use of Single Cytochrome P450 Enzymes in Drug Research
Softcover reprint of the original 1st ed. 1994
Book Details
Format
Paperback / Softback
Book Series
Ernst Schering Foundation Symposium Proceedings
ISBN-10
3662030217
ISBN-13
9783662030219
Edition
Softcover reprint of the original 1st ed. 1994
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint
Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Country of Manufacture
DE
Country of Publication
GB
Publication Date
Nov 23rd, 2012
Print length
227 Pages
Product Classification:
PharmacologyBiochemistry
Ksh 8,100.00
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Metabolic research and especially that which focuses on the monooxygenase cytochrome P450 system has gone through dramatic progressive changes within the last decade. Availability of highly sophisticated analytical techniques has contributed to increased molecular understanding of biotransformation pathways. Nowadays designer drugs are computer composable focussing on metabolic stability. The rapid development of recombinant enzymes has, in many cases, replaced the intensive work on P450 isolation from naturally occurring sources. Recombinant P450s can be expressed in cell lines and thus made available for reproducible and constant use addressig a large number of scientific questions. This book describes the present position of such research.
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