Atlas of Lymphoscintigraphy and Sentinel Node Mapping : A Pictorial Case-Based Approach

Although lymphoscintigraphy was originally introduced into clinical routine for identification of the cause of peripheral edema, more recently it has been widely applied for radioguided biopsy of the sentinel lymph node in patients with solid cancers.

Anatomy and physiology of lymphatic circulation.- Pathophysiology of lymphatic circulation in different disease conditions.- Methodological aspects of lymphoscintigraphy: radiopharmaceuticals and instrumentation.- Lymphoscintigraphy for the differential diagnosis of peripheral edemas.- Lymphoscintigraphy for the characterization of intracavitary lymph effusions.- The sentinel lymph node concept in oncologic surgery.- General concepts on radioguided sentinel lymph node biopsy: preoperative imaging, intraoperative gamma-probe guidance, intraoperative imaging, multimodality imaging.- SPECT/CT image generation and criteria of interpretation for sentinel lymph node mapping.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in breast cancer.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in cutaneous melanoma.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in head and neck cancers.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in non-small-cell lung cancer.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in cancers of the gastrointestinal tract.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in cancers of the female reproductive system.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in cancers of the male reproductive system.- Preoperative and intraoperative lymphatic mapping for radioguided sentinel node biopsy in kidney and bladder cancers.