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Bioassay Techniques for Drug Development

By: (Author) PakistanResearch Institute of Chemistry Karachi , (Author) M. Iqbal Choudhary , (Author) William J. Thomsen

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Ksh 31,500.00

Format: Hardback or Cased Book

ISBN-10: 9058230511

ISBN-13: 9789058230515

Publisher: Harwood-Academic Publishers

Imprint: Harwood-Academic Publishers

Country of Manufacture: GB

Country of Publication: GB

Publication Date: Oct 4th, 2001

Print length: 240 Pages

Weight: 616 grams

Dimensions (height x width x thickness): 15.70 x 23.70 x 2.10 cms

Product Classification: Pharmaceutical industries
Pharmacology
Scientific equipment, experiments & techniques

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A step-by-step look at how simple and rapid bioassays can serve as the starting point for drug discovery, cutting development time which is both long and expensive.
The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery and pharmacognosy. The contents detail a number of enzyme-based assays, cell-based functional bioassays and receptor radioligand binding assays along with detailed descriptions of each type. The majority of these bioassays are presented in a step-by-step format, so they could even be implemented by technical personnel with little background in microbiology, biochemistry or pharmacology.

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