Biosynthesis : Aromatic Polyketides, Isoprenoids, Alkaloids
Softcover reprint of the original 1st ed. 2000
Book Details
Format
Paperback / Softback
Book Series
Topics in Current Chemistry
ISBN-10
3642085830
ISBN-13
9783642085833
Edition
Softcover reprint of the original 1st ed. 2000
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint
Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Dec 6th, 2010
Print length
247 Pages
Product Classification:
Organic chemistryBiochemistryBiotechnology
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This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites).
This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.
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