Brain Hypoxia and Ischemia

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia.

I. Ion Channels, Transporters and Excitotoxicity.- Regulation of vulnerability to NMDA excitotoxicity during postnatal maturation.- Acidosis, acid-sensing ion channels, and glutamate receptor independent neuronal injury.- Brain ischemia and neuronal excitability.- Critical roles of the Na+/K+-ATPase in apoptosis and CNS Diseases.- Emerging role of water channels in regulating cellular volume during oxygen deprivation and cell death.- A zinc-potassium continuum in neuronal apoptosis.- Mitochondrial ion channels in ischemic brain.- II. Reactive Oxygen Species, and gene expression to behavior.- Perinatal panencephalopathy in premature infants: Is it due to hypoxia-ischemia?.- Effects of intermittent hypoxia on neurological function.- Brainstem sensitivity to hypoxia and ischemia.- Matrix metalloproteinases in cerebral hypoxia-ischemia.- Oxidative stress in hypoxic-ischemic brain injury.- Post-natal hypoxia and the developing brain: Cellular and molecular mechanisms of injury.- Hypoxia-inducible Factor 1.- Transcriptional response to hypoxia in developing brain.- Acute stroke therapy: Highlighting the ischemic penumbra.- Genes and survival to low O2 environment: Potential insights from Drosophila