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By: (Edited by) Jr. Putney , (Edited by) Juliusz Ashot Kozak
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This book focuses on methods to investigate the structure and function of non-voltage gated calcium channels. The book aims to present important discoveries in calcium entry pathways; specifically, chapters dealing with the molecular identification of store-operated calcium channels which were dealt with by earlier volumes in the Methods in Signal Transduction series. The calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels (Cav) have been studied extensively, the non-voltage gated calcium entry channel genes have been identified relatively recently.
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
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