Camdex-DS-II : A comprehensive assessment for diagnosing Alzheimer's disease

Diagnosis of prodromal Alzheimer's disease and AD dementia in people with Down's Syndrome is a major challenge. The comprehensive Cambridge Examination for Mental Disorders of Older People with DS and Others with Intellectual Disabilities (CAMDEX-DS) has been validated for diagnosing prodromal AD and AD dementia.

The CAMDEX-DS-II is a fully updated second edition of a validated assessment for diagnosing dementia in people with Down Syndrome (a group known to be at particular risk of dementia), as well as others with intellectual disabilities. In order to differentiate decline due to dementia or other mental health issues from pre-existing impairment, particular emphasis has been placed on establishing change from the individual?s best level of functioning. The CAMDEX-DS-II comprises a comprehensive manual including guidance for diagnosis, a structured informant interview to collect information about presenting symptoms and clinical history, a direct participant assessment (CAMCOG-DS-II), and a picture book to use in conjunction with the participant assessment. The CAMDEX-DS-II nmay be used in community settings by health professionals as part of the diagnostic process, or to formalise diagnosis in the context of research. The Informant Interview is a structured interview carried out in the absence of the person with Down Syndrome or other intellectual disabilities, with a relative or carer who has known them well over time.