This book classifies available tumor markers according to their principal characteristics and relative methodologies. It presents and discusses the use of the principal tumor markers available for the management of specific cancers (brain, head and neck, oral, gastrointestinal, lung and mesotelioma, urological, gynecological, thyroid, hematological, and melanoma). Each chapter focuses on one type of cancer and is written by physicians or scientists from various countries who blend their clinical experience and scientific expertise in new technologies to provide a definitive account of cancer biomarker discoveries.

Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers.

It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information.

The book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers.

• Presents noninvasive early molecular markers in urological cancers
• Describes gynecological and endocrine cancer markers
• Details noninvasive markers of breast, ovarian, cervical, and thyroid cancers
• Addresses hematological malignancies 
• Contains information on noninvasive molecular markers in myelodysplastic syndromes, acute myeloid leukemia, Hodgkin’s lymphoma, and multiple myeloma
• Provides comprehensive information on diagnostic and prognostic biomarkers in cutaneous melanoma

This text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.