Cell Cycle Control : New Research
Book Details
Format
Hardback
ISBN-10
1604567961
ISBN-13
9781604567960
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Oct 1st, 2008
Print length
496 Pages
Weight
1,018 grams
Dimensions
26.20 x 18.90 x 3.80 cms
Product Classification:
Developmental biology
KSh 36,000.00
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This book provides leading edge research on a cell cycle, which is an ordered and highly controlled set of events that leads to cell growth and proliferation. Cell cycle progression is driven by changes in the substrate specificity and subcellular localisation of cyclin-dependent kinases (Cdks), which in turn are modulated by a collection of cyclins, Cdk-activating and Cdk-inhibiting kinases, and Cdk inhibitors (CDKIs). Regulation of the cell cycle is critical for the normal development of multicellular organisms and dysregulation of cell cycle could lead to cancer, a disease where normal cell growth and behaviour are lost. Cell cycle regulation is tightly controlled by both synthesis and degradation of short-lived proteins, such as cyclins and CDKIs, and degradation of these proteins is mainly mediated by the ubiquitin-dependent proteasome pathway.
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