Chromosome Translocation
Softcover Reprint of the Original 1st 2018 ed.
Book Details
Format
Paperback / Softback
Book Series
Advances in Experimental Medicine and Biology
ISBN-10
9811344590
ISBN-13
9789811344596
Edition
Softcover Reprint of the Original 1st 2018 ed.
Publisher
Springer Verlag, Singapore
Imprint
Springer Verlag, Singapore
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Dec 29th, 2018
Print length
168 Pages
Product Classification:
Medical geneticsCellular biology (cytology)
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This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases. The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation. It is a valuable resource for students and researchers alike, providing insights into chromosome translocations and, potentially, other genomic aberrations involved in understanding and curing human diseases.
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