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Cluster Randomised Trials
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Cluster Randomised Trials

by Lawrence H. Moulton , Lawrence H. Moulton , Richard J. Hayes , Richard J. Hayes

Book Details

Format Paperback / Softback
Book Series Chapman & Hall/CRC Biostatistics Series
ISBN-10 1032339586
ISBN-13 9781032339580
Publisher Taylor & Francis Ltd
Imprint Chapman & Hall/CRC
Country of Manufacture GB
Country of Publication GB
Publication Date Jul 12th, 2022
Print length 424 Pages
Weight 640 grams
Dimensions 15.30 x 23.50 x 3.20 cms
Product Classification: Medical research Clinical trials Epidemiology & medical statistics Pharmacology Probability & statistics
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Cluster Randomised Trials, Second Edition explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, it covers basic concepts underlying the use of cluster randomisation.

Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, the book covers basic concepts underlying the use of cluster randomisation, such as direct, indirect, and total effects.

In the time since the publication of the first edition, the use of cluster randomised trials (CRTs) has increased substantially, which is reflected in the updates to this edition. There are greatly expanded sections on randomisation, sample size estimation, and alternative designs, including new material on stepped wedge designs. There is a new section on handling ordinal outcome data, and an appendix with descriptions and/or generating code of the example data sets.

Although the book mainly focuses on medical and public health applications, it shows that the rigorous evidence of intervention effects provided by CRTs has the potential to inform public policy in a wide range of other areas. The book encourages readers to apply the methods to their own trials, reproduce the analyses presented, and explore alternative approaches.

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