Book Details
Format
Paperback / Softback
ISBN-10
3030638162
ISBN-13
9783030638160
Edition
1st ed. 2021
Publisher
Springer Nature Switzerland AG
Imprint
Springer Nature Switzerland AG
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Feb 1st, 2021
Print length
107 Pages
Product Classification:
Biomedical engineeringBiotechnologyMaterials science
Ksh 8,100.00
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This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers.
This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization.
- Reviews state-of-the-art strategies for drug incorporation and retention in collagen;
- Covers collagen based material applications for improving vascularization and tissue regeneration;
- Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery.
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