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Computer-Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates
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Computer-Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates

Book Details

Format Paperback / Softback
ISBN-10 1032238771
ISBN-13 9781032238777
Publisher Taylor & Francis Ltd
Imprint CRC Press
Country of Manufacture GB
Country of Publication GB
Publication Date Dec 13th, 2021
Print length 146 Pages
Weight 270 grams
Ksh 9,200.00
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The authors focus on the properties of various lipopeptides which are produced as metabolites by bacteria and have shown to have antimicrobial properties. They provide a step-by-step method in identifying drug molecules for target compounds and testing various properties for drug efficacy. Both experienced researchers and beginners will benefit.

Increase in antibiotic resistance has forced researchers to develop new drugs against microorganisms. Lipopeptides are produced as secondary metabolites by some microorganisms. Computer-aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates provides the identification of novel ligands for different antimicrobial lipopeptides. Along with identification, it also provides some of the in silico drug design processes, namely homology modelling, molecular docking, QSAR studies, drug ADMET studies and pharmacophore studies to check the ligand-lipopeptide interaction. Some lipopeptides have shown anti-cancerous properties too, and this book discusses the required templates to design new drugs using computational techniques.

Key Features:

  • Focuses on the use lipopeptides as new antimicrobial compounds
  • Presents the basics of in silico modelling for design and development of new drug molecules, and is therefore of interest to beginners in the field
  • Provides a step-by-step process for identification of drug molecules and testing its efficacy in silico
  • Couples with courses on patents and intellectual property rights

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