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Computer Techniques in Preclinical and Clinical Drug Development
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Computer Techniques in Preclinical and Clinical Drug Development

Book Details

Format Hardback or Cased Book
ISBN-10 0849376823
ISBN-13 9780849376825
Publisher Taylor & Francis Inc
Imprint CRC Press Inc
Country of Manufacture US
Country of Publication GB
Publication Date Jul 23rd, 1996
Print length 256 Pages
Weight 1,000 grams
Ksh 37,800.00
Werezi Extended Catalogue 0 in stock

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This text responds to the question "how can we use computational methods to improve the success rate in drug development?" It aims to show how modelling makes it possible to extract the maximum amount of information and predictive value from preclinical data.
It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational methods to improve the success rate in drug development?" Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

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