Design of Enzyme Inhibitors as Drugs, Volume 2
Book Details
Format
Hardback or Cased Book
ISBN-10
0192621343
ISBN-13
9780192621344
Publisher
Oxford University Press
Imprint
Oxford University Press
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Apr 21st, 1994
Print length
848 Pages
Weight
1,422 grams
Dimensions
23.70 x 16.50 x 5.40 cms
Ksh 55,100.00
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A text on the developments in the design of enzyme inhibitors as potent drugs for the treatment of disease and infection. This type of drug exerts its action by modifying a particular body function or combating an infection by blocking the action of a specific enzyme.
A high proportion of drugs currently coming to market exert their action in the body by inhibition of a target enzyme involved in a particular body function or in a bacterium, protozoon, or virus causing an infection. This book extends the previous volume in providing a comprehensive coverage of more recently recognised target enzymes and their known inhibitors, and within this framework of knowledge demonstrates how the drug designer uses all available information to develop a specific therapeutic agent. Drug design is an interdisciplinary art and the text illustrates the pathway followed from the initial design concept and synthesis of an inhibitor through its in vitro and in vivo assessments to clinical trial, a process involving chemists, biochemists, pharmacologies, and clinicians.
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