Epigenetic Alterations in Oncogenesis
2012 ed.
Book Details
Format
Hardback or Cased Book
Book Series
Advances in Experimental Medicine and Biology
ISBN-10
1441999663
ISBN-13
9781441999665
Edition
2012 ed.
Publisher
Springer-Verlag New York Inc.
Imprint
Springer-Verlag New York Inc.
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Sep 6th, 2012
Print length
348 Pages
Weight
666 grams
Dimensions
24.40 x 16.60 x 2.60 cms
Product Classification:
Medical geneticsOncology
Ksh 23,400.00
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The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures.
The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.
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