Excitatory Amino Acids : Clinical Results with Antagonists
Book Details
Format
Hardback or Cased Book
ISBN-10
0125468202
ISBN-13
9780125468206
Publisher
Elsevier Science Publishing Co Inc
Imprint
Academic Press Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Jan 10th, 1997
Print length
156 Pages
Weight
342 grams
Ksh 30,600.00
Manufactured on Demand
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Presenting the results of human testing of modulators of excitatory amino acid neurotransmitters, this book provides coverage of the field of excitatory amino acids from synaptic function to preclinical and clinical pharmacology. It gives a description of the development of NMDA (Nmethyl-d-aspartate) and non-NMDA antagonists.
Glutamate is the major excitatory neurotransmitter in the brain and dysfunction of glutamate transmission is the likely cause of a variety of diseases including neurodegeneration following cerebral ischemia, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, spasticity, emesis, chronic pain, and schizophrenia. Excitatory amino acid receptor agonists and antagonists are therefore of major interest as potential drugs for central nervous system disorders. Excitatory Amino Acids is the first book entirely dedicated to the results of human testing of modulators of excitatory amino acid neurotransmitters.
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