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Exploring Pancreatic Metabolism and Malignancy
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Exploring Pancreatic Metabolism and Malignancy

2019 ed.

Book Details

Format Paperback / Softback
ISBN-10 9813293950
ISBN-13 9789813293953
Edition 2019 ed.
Publisher Springer Verlag, Singapore
Imprint Springer Verlag, Singapore
Country of Manufacture GB
Country of Publication GB
Publication Date Dec 10th, 2020
Print length 268 Pages
Product Classification: MetabolismOncologyImmunologyDiabetes
Ksh 16,200.00
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This book comprehensively describes the association between metabolic syndrome and pancreatic cancer progression, and the mechanism of action and target definition with a view to drug discovery.
This book comprehensively describes the association between metabolic syndrome and pancreatic cancer progression, and the mechanism of action and target definition with a view to drug discovery. Metabolic syndrome, which includes adnominal obesity, hypertension, dyslipidemia, and hyperglycemia, has recently been shown to play an important role in the etiology and progression of various cancers. Further, obesity and diabetes have been associated with an increased incidence of gastric cancers.

The book reviews the key biological mechanisms underlying the association between metabolic dysregulation, including obesity-associated enhancement of growth factor signaling, inflammation, and perturbation in pancreatic cancer cell growth and metastasis. It also illustrates the role of the inflammatory signaling pathway in metabolic diseases as well as tumor growth and explores the potential of these pathways as the rational targets for pancreatic cancer therapy.

Lastly, the book offers a comprehensive description of the challenges associated with diabetes and pancreatic cancer therapy.

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