Genetic Association Studies : Background, Conduct, Analysis, Interpretation

Genetic Association Studies is designed for students of public health, epidemiology, and the health sciences who need a non-mathematical introduction to genetic epidemiology. It provides a multi-faceted approach to genetic association studies covering molecular genetics, epidemiology, and statistics as a foundation for genetic associations. Both candidate gene and genome-wide studies are included as well as bioinformatics approaches to the interpretation of results.

Genetic Association Studies is designed for students of public health, epidemiology, and the health sciences, covering the main principles of molecular genetics, population genetics, medical genetics, epidemiology and statistics. It presents a balanced view of genetic associations with coverage of candidate gene studies as well as genome-wide association studies. All aspects of a genetic association study are included, from the lab to analysis and interpretation of results, but also bioinformatics approaches to causality assessment. The role of the environment in genetic disease is also highlighted. Genetic Association Studies will enable readers to understand and critique genetic association studies and set them on the way to designing, executing, analyzing, interpreting, and reporting their own.