Genetic Variants in Alzheimer's Disease
2013 ed.
Book Details
Format
Hardback or Cased Book
ISBN-10
146147308X
ISBN-13
9781461473084
Edition
2013 ed.
Publisher
Springer-Verlag New York Inc.
Imprint
Springer-Verlag New York Inc.
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Jun 22nd, 2013
Print length
254 Pages
Weight
534 grams
Dimensions
23.90 x 16.20 x 2.00 cms
Ksh 23,400.00
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Alzheimer’s Disease is the most common form of dementia. This has resulted in the identification of nine new genes and perhaps more importantly the realization that new pathways could be involved in the pathogenesis of Alzheimer’s. The aim of this book is to put all of the recent genetic data on these new genes into context.
Alzheimer’s Disease is the most common form of dementia. The disease is characterised by the loss of synapses and neurons in the cerebral cortex and certain subcortical regions. In the last three years, the genetics of Alzheimer’s Disease has made significant advances; in fact, one could argue more than in the previous two decades. This has resulted in the identification of nine new genes and perhaps more importantly the realization that new pathways could be involved in the pathogenesis of Alzheimer’s. These new pathways are now legitimate targets for therapeutic intervention, which can possibly lead to treatment or a possible cure. The aim of this book is to put all of the recent genetic data on these new genes into context. Different genetic variants will be discussed, as well as biomarkers and future possibilities. ?
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