Genomic Disorders : The Genomic Basis of Disease
Softcover reprint of hardcover 1st ed. 2006
Book Details
Format
Paperback / Softback
ISBN-10
1617376426
ISBN-13
9781617376429
Edition
Softcover reprint of hardcover 1st ed. 2006
Publisher
Humana Press Inc.
Imprint
Humana Press Inc.
Country of Manufacture
US
Country of Publication
GB
Publication Date
Dec 9th, 2010
Print length
426 Pages
Product Classification:
Pathology
Ksh 18,000.00
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A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
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