Glia & Inflammation in Neurodegenerative Disease
Book Details
Format
Hardback or Cased Book
ISBN-10
1594549842
ISBN-13
9781594549847
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Feb 5th, 2007
Print length
275 Pages
Weight
826 grams
Dimensions
26.30 x 18.40 x 2.40 cms
Product Classification:
ImmunologyNeurology & clinical neurophysiology
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The brain has long been considered an immune privileged organ, meaning that inflammatory cells are excluded due to a relatively impenetrable blood brain barrier (BBB). However, this is not to say that the central nervous system is incapable of eliciting immune responses, as resident inflammatory cells exist within the brain parenchyma. Microglia have long been thought to be the brain''s resident immune cell with myeloid lineage similar to monocytes and macrophages. In this volume, the authors review the current state of knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. The changing role of inflammation with development is considered. They also present a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level.
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