Glycoscience: Basic Science to Applications : Insights from the Japan Consortium for Glycobiology and Glycotechnology (JCGG)

This book presents the state of the art in glycoscience and proposes a road map for the coming decade, focusing on the potential of glycoscience research to shed light on important basic science issues and give rise to exciting new applications, especially in the field of diagnosis and therapeutics.

Introducion.- Part. 1. Future technological advances to elucidate the structures and functions of glycans.- Chapter 1. Structural analysis of glycans (analytical and detection methods).- Chapter 2. Structural biology of glycans.- Chapter 3. Chemical and enzymatic synthesis and production of glycans.- Chapter 4. Technologies to elucidate functions of glycans.- Part 2. Glycans and biopharmaceuticals.- Chapter 1. Antibody pharmaceuticals.- Chapter 2. Standard glycan library.- Chapter 3. Mass production in silk worm and yeast.- Chapter 4. Glycoengineering.- Chapter 5. Glycomimetics.- Chapter 6. Glycan vaccine.- Part 3.  Sugar chains (Glycans) involved in medical science and medical care.- Chapter 1. Glycan function in development and evolution.- Chapter 2. Glycans in nervous system.- Chapter 3. Glycans in osseous tissue and articulation.- Chapter 4. Glycans in infection and immunity.- Chapter 5. Next generation medical care.- Chapter 6.  Life-style related disease and aging.- Chapter 7.  Congenital disorders of glycosylation (CDG), neuromuscular related diseases.- Chapter 8.   Glycan biomarkers for cancer and various disease.- Part 4.  Food implicated in glycans and its function.- Part 5. Glycan-related materials and their use for biomaterials.- Part 6. Educational materials and training for glycosciences.