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Glycosphingolipids Signaling
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Glycosphingolipids Signaling

2020 ed.

Book Details

Format Paperback / Softback
ISBN-10 9811558094
ISBN-13 9789811558092
Edition 2020 ed.
Publisher Springer Verlag, Singapore
Imprint Springer Verlag, Singapore
Country of Manufacture GB
Country of Publication GB
Publication Date Jan 25th, 2022
Print length 181 Pages
Ksh 23,400.00
Werezi Extended Catalogue 0 in stock

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Cellular GSLs are associated with many biological functions such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell–cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein–carbohydrate or carbohydrate–carbohydrate interactions.

This book presents the latest knowledge and the most recent research results on glycosphingolipid (GSL)-mediated signaling. GSLs are important constituents of the plasma membrane that exert their distinct functions through binding to certain functional proteins. They play a role in various human diseases and also function as human alloantigens. Cellular GSLs are associated with many biological functions such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell-cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein-carbohydrate or carbohydrate-carbohydrate interactions. This book opens by providing the key background on GSL glycan-receptor interactions and mammalian GSL synthesis. Up-to-date information is then presented on all aspects of GSL-dependent signaling. Viral protein and bacterial toxin protein interactions with host cell GSLs are examined in depth, and the concluding chapter is devoted to signaling regulation. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.


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