HER2 and Cancer : Mechanism, Testing and Targeted Therapy
Book Details
Format
Hardback or Cased Book
ISBN-10
1611226503
ISBN-13
9781611226508
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Oct 1st, 2011
Print length
245 Pages
Weight
694 grams
Dimensions
26.00 x 18.60 x 2.20 cms
Product Classification:
Environmental science, engineering & technologyEnvironmental science, engineering and technology
Ksh 47,150.00
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The HER2 receptor is a 185-kDa transmembrane glycoprotein with tyrosine kinase activity, and belongs in the human epidermal growth factor receptor (HER) family consisting of four members. Moreover, aberrant HER2 protein overexpression has been linked to various human gynecological adenocarcinomas, including breast, endometrium, ovary and cervix, and has been found to be a poor prognostic factor for survival. This new book presents topical research in the study of HER2, including targeting HER2 with photodynamic therapy; HER2 shedding as a biomarker in breast cancer; development of trastuzumab resistance and targeted nanomedicines conjugated with HER2 antibodies in cancer therapy.
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