Huntington''s Disease : Symptoms, Risk Factors & Prognosis
Book Details
Format
Paperback / Softback
ISBN-10
1628083166
ISBN-13
9781628083163
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Aug 1st, 2013
Print length
121 Pages
Weight
222 grams
Dimensions
22.20 x 15.90 x 0.90 cms
Product Classification:
Neurosciences
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Huntington''s disease (HD) is a progressive, neurodegenerative genetic disorder characterised by motor dysfunctions, cognitive decline, and psychiatric symptoms. In this book, the authors discuss the symptoms, risk factors and prognosis in Huntington''s disease. Topics include the pathogenic mechanisms by which the expanded polyglutamine huntingtin causes neuronal dysfunction and death and the potential therapeutic strategies recently developed for this incurable disorder; the role of brain-derived neurotrophic factor in Huntington''s disease; and the legal ramifications in relation to evolving impairments of capacity which can have an outcome in terms of involuntary status as mental health patients, testamentary capacity and the need for guardianship and administration orders.
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