Hypospadias and Genital Development
Book Details
Format
Hardback or Cased Book
Book Series
Advances in Experimental Medicine and Biology
ISBN-10
0306481774
ISBN-13
9780306481772
Publisher
Kluwer Academic Publishers Group
Imprint
Kluwer Academic / Plenum Publishers
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Mar 1st, 2004
Print length
400 Pages
Weight
670 grams
Dimensions
18.40 x 26.30 x 2.10 cms
Ksh 12,950.00
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Congenital anomalies of the genitalia are the second most common birth abnormality besides congenital heart defects. Genital anomalies come in many varieties with the most common abnormality being hypospadias. This book focuses on the basic science research of hypospadias and genital development.
Section I. Human Studies.- Epidemiology of Hypospadias.- Endocrine Evaluation of Hypospadias.- Endocrine Abnormalities in Boys with Hypospadias.- Genetic and Clinical Studies on Hypospadias.- Section II. Mechanism of Genital Development.- Development of the Penile Urethra.- Anatomical Studies of the Mouse Genital Tubercle.- Anatomical Studies of the Fibroblast Growth Factor-10 Mutant, Sonic Hedge Hog Mutant, and Androgen Receptor Mutant Mouse Genital Tubercle.- Developmental Genetics of Hypospadias.- Development of the Mouse External Genitalia: Unique Model of Organogenesis.- New Concepts on the Development of the Vagina.- Section III. Endocrine Disruptors and Sexual Dimorphism in the Animal Kingdom.- Endocrine Disruption Overview: Are Males at Risk?.- Endocrine Disruption and Hypospadias.- Toxicant-Induced Hypospadias in the Male Rat.- Masculinization of Female Mammals: Lessons from Nature.
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