Immunogenetics
Book Details
Format
Paperback / Softback
ISBN-10
1617614785
ISBN-13
9781617614781
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Aug 26th, 2011
Print length
77 Pages
Weight
160 grams
Dimensions
15.50 x 23.00 x 0.60 cms
Product Classification:
Cellular biology (cytology)
Ksh 11,150.00
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The Human Genome Project has facilitated the identification of various genetic regions associated with disease susceptibility. This identification step is important as it yields clues into the pathways implicated in defining disease susceptibility and may uncover important therapeutic targets. Indeed, by performing genome-wide scans, one can identify many genetic loci associated with auto-immune disease susceptibility. However, the odds ratio of each locus is relatively low. Therefore, the limitation of these studies is in the biological translation of the data. This raises the question of how one verifies the true biological impact that each of these genetic variations has on human disease. This book presents an alternative strategy for the identification of various genetic regions associated with disease susceptibility.
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