Immunoreceptor Tyrosine-based Inhibition Motifs

This volume contains 15 reviews written by authors who made significant contributions to the identification of ITIM-bearing molecules and the study of their biological properties.

List of Contents.- Biology of Immunoreceptor Tyrosine-based Inhibition Motif-Bearing Molecules.- Negative Regulation of Hematopoietic Cell Activation and Proliferation by Fc?RIIB.- The Role of the SRC Homology 2-Containing Inositol 5?-Phospatase in Fc?Rl-Induced Signaling.- The Unexpected Complexity of Fc?RIIB Signal Transduction.- Regulation of B Cell Antigen Receptor Signaling by the Lyn/CD22/SHP1 Pathway.- HLA-Specific and Non-HLA-Specific Human NK Receptors.- Regulation of NK Cell Functions Through Interaction of the CD94/NKG2 Receptors with the Nonclassical Class I Molecule HLA-E.- Inhibitory Role of Murine Ly49 Lectin-like Receptors on Natural Killer Cells.- gp49: An Ig-like Receptor with Inhibitory Properties on Mast Cells and Natural Killer Cells.- A Novel Family of Inhibitory Receptors for HLA Class I Molecules That Modulate Function of Lymphoid and Myeloid Cells.- Interactions of LIRs, a Family of Immunoreceptors Expressed in Myeloid and Lymphoid Cells, with Viral and Cellular MHC Class I Antigens.- Paired Immunoglobulin-like Receptors of Activating and Inhibitory Types.- LAIR-1, a Widely Distributed Human ITIM-Bearing Receptor on Hematopoietic Cells.- The Mast Cell Function-Associated Antigen, a New Member of the ITIM Family.- The Enigma of Activating Isoforms of ITIM-Bearing Molecules.