Immunosuppressant Analogs in Neuroprotection
Softcover reprint of the original 1st ed. 2003
Book Details
Format
Paperback / Softback
ISBN-10
1468497421
ISBN-13
9781468497427
Edition
Softcover reprint of the original 1st ed. 2003
Publisher
Humana Press Inc.
Imprint
Humana Press Inc.
Country of Manufacture
US
Country of Publication
GB
Publication Date
Dec 3rd, 2012
Print length
378 Pages
Product Classification:
Neurology & clinical neurophysiology
Ksh 18,000.00
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An authoritative survey of the most recent scientific evidence showing how cyclosporin, FK-506, and their analogs-the neuroimmunophilins-evolved from being purely immunosuppressant "drugs" to neuroprotective "agents". The book focuses on recent preclinical evidence that demonstrates the neurotrophic/neuroprotective effects of immunosuppressants when administered alone or when combined with neural transplantation therapy in animal models of neurological disorders. It also discusses their efficacy and mechanisms of action in vitro and in vivo models of CNS disease, and provides laboratory studies with compelling clinical indications for Alzheimer's disease, Huntington's disease, stroke, traumatic brain injury, spinal cord injury, ALS, sciatic nerve injury, and drug addiction.
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