Inflammasomes : Mechanism of Action, Regulation & Role in Disease
Book Details
Format
Paperback / Softback
ISBN-10
1634848918
ISBN-13
9781634848916
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
May 1st, 2016
Print length
72 Pages
Weight
162 grams
Dimensions
15.60 x 24.60 x 1.00 cms
Product Classification:
Infectious & contagious diseasesImmunologyBiochemistryCellular biology (cytology)
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The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1β takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this fine-tuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections.
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