Insulin Receptor Substrate Signaling in the Central Nervous System
Book Details
Format
Paperback / Softback
ISBN-10
1616682558
ISBN-13
9781616682552
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Aug 26th, 2011
Print length
67 Pages
Weight
142 grams
Dimensions
15.50 x 23.00 x 0.60 cms
Product Classification:
Molecular biology
Ksh 9,550.00
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Recent advance in molecular biology revealed new insights into the function of insulin receptor signalling and insulin receptor substrate (IRS) protein mediated signals in the central nervous system (CNS) in vivo. The IRS proteins mediate mainly intracellular effects of the insulin-like growth factor-1 receptor (IGF-1R) and the insulin receptor (IR). The functions of IRS proteins in peripheral tissues like muscle, liver, pancreas and fat have been characterised in detail. This book examines why IRS signalling is not only critical during brain development, but also for reproduction, energy homeostasis, ageing and possibly for neurodegenerative diseases in humans.
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