Interferons : Characterization, Mechanism of Action & Clinical Applications
Book Details
Format
Hardback or Cased Book
ISBN-10
1620812983
ISBN-13
9781620812983
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Oct 19th, 2012
Print length
172 Pages
Weight
552 grams
Dimensions
26.10 x 18.30 x 1.60 cms
Product Classification:
Immunology
Ksh 36,000.00
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Interferons are cytokines that are very important in regulating both innate and adaptive immune response. Of the two different types of interferons, Type I interferons are potent mediators of the innate immune response against viruses and cancer. Type II interferons, mainly IFN-y enhances T cell polarisation in the lymph nodes that result in their expansion. This book discusses the characterisation, mechanisms of action and clinical applications of interferons. Topics include interferon-gamma, oligodendrocyte injury and inflammatory demyelination; the role of IFN-y in oesophageal squamous cell carcinoma; interferons in multiple sclerosis; the effect of interferons on NK cell activity in HIV infection and tumour cell development; and understanding the mechanisms of interaction between serine proteases, serine protease receptors and interferons.
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