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Introduction to Synthetic Biology
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Introduction to Synthetic Biology : About Modeling, Computation, and Circuit Design

2018 ed.

Book Details

Format Paperback / Softback
ISBN-10 9811087512
ISBN-13 9789811087516
Edition 2018 ed.
Publisher Springer Verlag, Singapore
Imprint Springer Verlag, Singapore
Country of Manufacture SG
Country of Publication GB
Publication Date May 24th, 2018
Print length 187 Pages
Weight 388 grams
Dimensions 17.10 x 23.90 x 0.80 cms
Ksh 14,400.00
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The textbook is based on the lectures of the course “Synthetic Biology” for Master’s students in biology and biotechnology at the Harbin Institute of Technology. The goal of the textbook is to explain how to make mathematical models of synthetic gene circuits that will, later on, drive the circuit implementation in the lab.
The textbook is based on the lectures of the course “Synthetic Biology” for Master’s students in biology and biotechnology at the Harbin Institute of Technology. The goal of the textbook is to explain how to make mathematical models of synthetic gene circuits that will, later on, drive the circuit implementation in the lab. Concepts such as kinetics, circuit dynamics and equilibria, stochastic and deterministic simulations, parameter analysis and optimization are presented. At the end of the textbook, a chapter contains a description of structural motifs (e.g. positive and negative feedback loops, Boolean gates) that carry out specific functions and can be combined into larger networks. Moreover, several chapters show how to build up (an analyse, where possible) models for synthetic gene circuits with four different open-source software i.e. COPASI, XPPAUT, BioNetGeN, and Parts & Pools-ProMoT.

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