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Introductory Adaptive Trial Designs : A Practical Guide with R

By: (Author) Mark Chang

Werezi Extended Catalogue
Delivery in 34 days

Ksh 13,500.00

Format: Hardback or Cased Book

ISBN-10: 1498717462

ISBN-13: 9781498717465

Publisher: Taylor & Francis Inc

Imprint: Chapman & Hall/CRC

Country of Manufacture: GB

Country of Publication: GB

Publication Date: Jun 8th, 2015

Print length: 232 Pages

Weight: 542 grams

Dimensions (height x width x thickness): 16.30 x 26.20 x 2.00 cms

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Taking a learning-by-doing approach, this tutorial-style book helps newcomers quickly and easily grasp the essence of adaptive designs as well as the foundations of adaptive design methods. It reduces the mathematics to a minimum and makes the material as practical as possible. The author includes R functions that enable readers to better understand the algorithms and customize the designs to meet their needs. For those with no R experience, an appendix provides a 30-minute R tutorial.

All the Essentials to Start Using Adaptive Designs in No Time





Compared to traditional clinical trial designs, adaptive designs often lead to increased success rates in drug development at reduced costs and time. Introductory Adaptive Trial Designs: A Practical Guide with R motivates newcomers to quickly and easily grasp the essence of adaptive designs as well as the foundations of adaptive design methods.





The book reduces the mathematics to a minimum and makes the material as practical as possible. Instead of providing general, black-box commercial software packages, the author includes open-source R functions that enable readers to better understand the algorithms and customize the designs to meet their needs. Readers can run the simulations for all the examples and change the input parameters to see how each input parameter affects the simulation outcomes or design operating characteristics.





Taking a learning-by-doing approach, this tutorial-style book guides readers on planning and executing various types of adaptive designs. It helps them develop the skills to begin using the designs immediately.


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