Ion Mobility Spectrometry

Beginning with a thorough discussion of the fundamental theories and physics of ion mobility, this third edition continues with a detailed description of the technology and applications. It discusses the recent advances in instrumentation and newly pioneered applications. Each chapter is thoroughly updated, with new information on present trends in IMS and coverage of FAIMS and DMS/MS. Significant expansion to the Biological and Biomedical section is provided, with an emphasis on LC ESI Mobility MS or ESI Mobility MS, including IMS TOF.

Since the turn of the twenty-first century, applications of ion mobility spectrometry (IMS) have diversified, expanding their utility in the military and security spheres and entering the realms of clinical practice and pharmaceutical exploration. Updated and expanded, the third edition of Ion Mobility Spectrometry begins with a comprehensive discussion of the fundamental theory and practice of IMS. Divided into four sections—Overview, Technology, Fundamentals, and Applications—the authors treat innovations and advances in all aspects of IMS in a fresh, thorough, and revised format.

Mobility-based methods are no longer restricted to volatile substances and indeed the many benefits of this technology—simplicity, convenience, and the low cost of technology—have become recognized as meritorious in a wide range of uses. This is also true for the advantages of measurements—high speed, distinctive spectral features, and operation in ambient pressure with thermalized ions. Ion Mobility Spectrometry, Third Edition serves specialists in the field of IMS who are interested in the potential of recent developments and researchers, engineers, and students who want a comprehensive overview of this technology.