Laboratory Animal Medicine

Laboratory Animal Medicine, Fourth Edition—a volume in the American College of Laboratory Animal Medicine (ACLAM) blue book series—is the authoritative reference on the biology, health, and care for species involved in research. Edited by recognized veterinary, operational, and research experts and endorsed as the official material for veterinary specialty certification by ACLAM, this work defines the standard for all aspects of humane laboratory animal care and science with animal models. This new edition contains significant changes in content and organization to reflect the evolution of the field. The animal welfare chapter has been moved to the beginning of the book to highlight this subject’s importance. Other chapters have either been consolidated to encourage the reader to recognize commonalities such as those between guinea pigs, gerbils and hamsters, or separated out in recognition of expansions in knowledge and cross-species complexity as illustrated by separate new and old world primate chapters. Advances in practice, technology, and knowledge are highlighted in the chapters on genetically modified organisms, with updates on new techniques in genetic engineering and consideration of non-rodent genetically modified models; microbiological monitoring, with an increased emphasis on environmental monitoring and sentinel free colony health monitoring methods; regulatory compliance, with a comprehensive chapter on birds; employee health and safety, with expanded consideration of compassion fatigue; and animal models in biomedical research, with increased emphasis on experimental design and rigor. New chapters on animal models for microbiome, infectious disease, and transplant research have been added to serve as a reference for the community. This book is an excellent reference for veterinarians and research scientists, as well as program directors and facility managers employed in a variety of academic and corporate settings. This edition continues the tradition of this text in setting standards for the research animal science community as well as expanding and updating relevant and essential topics for this specialty field.

Laboratory Animal Medicine, Fourth Edition – A volume in the American College of Laboratory Animal Medicine (ACLAM) blue books series – is the most authoritative reference on Laboratory Animals biology, health, and care. Edited by recognized experts in laboratory animal science, endorsed as the official material for certification by ACLAM, this reference defines the standard for all aspects of humane animal use and scientific investigations. This new edition implements significant changes in the area. The Animal Welfare chapter moved to the beginning of the book, highlighting this subject’s importance, and was expanded to include Euthanasia, previously covered on the anesthesia chapter. Further updates include the addition of hamsters & gerbils to the Guinea Pig chapter, the woodchuck and chinchillas are now included in the other rodents’ chapter, instead of a dedicated chapter. The non-human primates’ chapter was separated into two chapters: New and Old-World primates. The zebra finch and quail chapters were combined and now also include pigeons. The chapter on genetically modified animals was expanded to include additional CRISPR manipulation and genetic monitoring in key model species. The Microbiome Research chapter was added to account for this key factor and its importance in research. A chapter on transplant medicine was added and also covers xenozoonoses. The species-specific chapters are written at a level suitable for veterinarians and research scientists. Management chapters are suitable for program directors and facility managers both in academic and corporate settings. This edition continues the tradition of Laboratory Animal Medicine in setting the standards for the Laboratory Animal Science community, expanding, and updating the coverage following current and future practice in the area.