Lymphatic Metastasis and Sentinel Lymphonodectomy : Future Perspectives

I. Clinical Assessment of Lymph Node Metastases.- Efficacy of Immunoscintigraphy for Detection of Lymph Node Metastases.- Sensitivity and Specificity of Positron Emission Tomography (PET) for the Diagnosis of Lymph Node Metastases.- Diagnosis and Staging of Lymph Node Metastases.- Detection and Relevance of Immunohistochemically Identifiable Tumor Cells in Lymph Nodes.- II. Principles of Lymphatic Metastasis.- Cell Biology of Lymphatic Metastases: The Potential Role of c-erbB Oncogene Signalling.- The Lymph Node as a Bridgehead in the Metastatic Dissemination of Tumors.- Functional Anatomy of Lymphatic Vessels Under the Aspect of Tumor Invasion.- Molecular Diagnosis of Head and Neck Cancer.- III. Principles of Lymphatic Mapping and Sentinel Node Detection.- The Concept of the Sentinel Lymph Node.- Sentinel Node Localization by Lymphoscintigraphy: A Reliable Technique with Widespread Applications.- Vital Dye and Radiolabelled Colloids - Complement or Alternative.- IV. Sentinel Node Detection in Urogenital Cancer.- Application of the Sentinel Node Concept in Urogenital Cancer.- Intraoperative Lymphatic Mapping and Sentinel Node Identification: Gynecologic Applications.- V. Sentinel Node Detection in Malignant Melanoma.- Sentinel Node Detection in Malignant Melanoma.- Adjuvant Therapy of Malignant Melanoma and the Role of Sentinel Node Mapping.- VI. Sentinel Node Detection in Neck and Thyroid Cancer.- Selective Neck Dissection and Sentinel Node Biopsy in Head and Neck Squamous Cell Carcinomas.- Sentinel Lymph Node Dissection for Thyroid Malignancy.- Lymphoscintigraphy and Ultrasound Guided Fine Needle Aspiration Cytology of Sentinel Lymph Nodes in Head and Neck Cancer Patients.- VII. Sentinel Node Detection in Breast Cancer.- Present and Future of Sentinel Node Lymphadenectomy in Breast Cancer.- Specification of Potential Indications and Contraindications of Sentinel Lymph Node Biopsy in Breast Cancer.- Potential and Pitfalls of Sentinel Node Detection in Breast Cancer.- VIII. Sentinel Node Detection in Gastric Cancer.- Gastric Lymphography and Detection of Sentinel Nodes.- Potential and Futility of Sentinel Node Detection for Gastric Cancer.- IX. Sentinel Node Detection in Colorectal Cancer.- Probe Guided Surgery for Colorectal Cancer.- Identification of Lymph Node Metastases in Recurrent Colorectal Cancer.- Fluorescence as a Concept in Colorectal Lymph Node Diagnosis.