MALDI Mass Spectrometry Imaging : From Fundamentals to Spatial Omics

This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.

This book gathers, in a single resource, fundamental and applied knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging. It includes fundamentals in the MALDI ionisation process, different source geometries and capabilities, detection systems and the latest research and applications in a range of –omics areas as well as other broader areas. Chapters touch on dedicated sample preparation protocols specific to the class of compounds of interest, instrumentation used with strengths and current limitations, strategies for structural analysis and identification and applications. It will be a welcomed addition to the literature in this fast-moving field and provide a guide to new innovations and applications especially in spatial metabolomics and proteomics, among others. With contributions from leading experts, this book is an authoritative guide to this method. It is aimed at postgraduate and professional researchers in academia and in the industrial market, where it has direct application to (pre) clinical research. It will be a supporting volume for those just entering the field as well as experienced practitioners.