Microbiota and Clinical Disorders: Neuroimmunology to Cardio-Pulmonary Links

In recent years, the human microbiota has emerged as a critical regulator at the intersection of neuroimmunology, cardiovascular health, and pulmonary function. Microbiota and Clinical Disorders: Neuroimmunology to Cardio-Pulmonary Links brings together a comprehensive and clinically grounded exploration of how microbial communities influence a wide spectrum of neurological, psychiatric, cardiovascular, respiratory, and dermatological disorders. This volume begins by examining the role of microbiota in neuroimmunological and neurodegenerative conditions, including multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, epilepsy, and autism spectrum disorders. Subsequent chapters delve into the growing evidence linking microbiota alterations to psychiatric conditions such as anxiety, depression, schizophrenia, bipolar disorder, ADHD, obsessive–compulsive disorder, and circadian rhythm disturbances, highlighting the gut–brain axis as a central pathway in disease pathophysiology. Extending beyond the nervous system, the book addresses the impact of microbiota on cardiovascular disorders, including hypertension, coronary artery disease, heart failure, and cardiac rhythm abnormalities. The cardio-pulmonary continuum is further explored through in-depth discussions on asthma, chronic obstructive pulmonary disease, cystic fibrosis, bronchiectasis, sarcoidosis, and respiratory tract infections, underscoring the microbiota’s role in systemic inflammation and immune modulation. The final sections broaden the clinical scope by examining microbiota-related mechanisms in dermatological conditions such as atopic dermatitis, acne, and fungal skin infections. By integrating experimental findings with clinical perspectives, this book provides a multidimensional understanding of microbiota-driven disease processes. Designed for clinicians, researchers, and graduate-level students, Microbiota and Clinical Disorders: Neuroimmunology to Cardio-Pulmonary Links offers an authoritative resource that bridges basic science and clinical medicine, emphasizing the microbiota as a unifying factor across diverse clinical disorders.