Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates

This text provides summaries of the main systems of blood group antigens and MHC molecules. The human systems are used to explain the necessary background knowledge and the systems in nonhuman primates are then described and compared.

I Taxonomy and Phylogeny of Primates.- 1 Taxonomy and Phylogeny of Primates.- II Red Blood Cell Antigens.- 1 Introduction.- 2 The ABO, Hh and Lewis Blood Group in Humans and Nonhuman Primates.- 3 The MNSs Blood Group System Serology and Formal Genetics.- Molecular Biology of Glycophorins in Humans and Nonhuman Primates.- 4 The Rhesus System.- 5 The Duffy Blood Group System and Its Extensions in Nonhuman Primates.- 6 The ?-Galactosyl Epitope (Gal?1-3Gal?1-4G1cNAc-R) and the Natural Anti-Gal Antibody.- 7 Simian-Type Blood Groups of Nonhuman Primates.- 8 Blood Group Antigens as Receptors for Pathogens.- 9 Evolution of Blood Group Antigen Polymorphism.- III Major Histocompatibility.- 1 Geography and History of the Genes in the Human MHC: Can We Predict MHC Organization in Nonhuman Primates?.- 2 Class I Genes in Nonhuman Primates.- 3 Mhc Class II Genes of Nonhuman Primates The DR Loci.- Evolution of Length Variation in the Primate Mhc-DR Subregion.- The DQ Loci.- Nonhuman Primate Mhc-DP Genes.- The DM and DN/DO Loci.- 4 The Primate Class III Major Histocompatibility Complex Region Encoding Complement Components and Other Genes.- 5 Mhc Genes, Immune Response, and Vaccines.- 6 MHC and Disease Associations in Nonhuman Primates.- 7 Nonhuman Primate MHC Class I Sequences, 1997.- 8 Nonhuman Primate MHC Class II Sequences: A Compilation.- 9 Nomenclature for the Major Histocompatibility Complexes and Alleles of Different Nonhuman Primate Species.