Molecular Chaperones of the Endoplasmic Reticulum
Book Details
Format
Paperback / Softback
ISBN-10
161668173X
ISBN-13
9781616681739
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Sep 17th, 2010
Print length
126 Pages
Weight
224 grams
Dimensions
22.80 x 15.00 x 0.90 cms
Product Classification:
ProteinsCellular biology (cytology)
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An important function of the endoplasmic reticulum is the folding of newly synthesised polypeptide chains. Several general and specialised chaperones operate in the endoplasmic reticulum to assist protein folding. This book reviews our current knowledge of molecular chaperones of the ER, including the HSP70 class chaperones BiP and GRP170, their DnaJ and GrpE co-chaperones, the HSP90 class chaperone GRP94, and the lectin chaperones calnexin, calmegin, and calreticulin. This book provides an overview of the biochemistry and physical chemistry of molecular chaperones with emphasis on molecular chaperones of the endoplasmic reticulum.
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