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Multimodal Biomarkers for Central Nervous System Disorders : Development, Validation, and Clinical Integration: Proceedings of a Workshop

By: (Author) Board on Health Sciences Policy , (Author) and Medicine National Academies of Sciences Engineering , (Author) Forum on Neuroscience and Nervous System Disorders , (Author) Health and Medicine Division , (Edited by) Eva Childers , (Edited by) Sarah Carter , (Edited by) Sheena M. Posey Norris

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Ksh 3,250.00

Format: Paperback / Softback

ISBN-10: 0309708478

ISBN-13: 9780309708470

Publisher: National Academies Press

Imprint: National Academies Press

Country of Manufacture: GB

Country of Publication: GB

Publication Date: Nov 19th, 2023

Print length: 82 Pages

Product Classification: Medicine

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A key step towards reducing the burden of central nervous system (CNS) disorders is the identification of disease-specific biomarkers that can help predict, monitor, and guide treatment development. Recent technological advances have led to an increased number of biomarkers for different CNS disorders, providing the opportunity to generate multimodal biomarkers. While multimodal biomarkers can serve as promising tools to better diagnose and make accurate disease assessments, there remain challenges in current data collection, standardization, and validation practices that impede in their development. Recognizing the need for increased CNS biomarker integration, the National Academies Forum on Neuroscience and Nervous System Disorders hosted a public workshop in March 2023 to explore steps toward this goal, including data collection for biomarker discovery, development, validation, and assessment of clinical utility. This Proceedings of a Workshop summarizes the discussions held during the workshop. Table of ContentsFront Matter1 Introduction and Background2 Multimodal Biomarkers for Central Nervous System Disorders3 Exploring the State of the Science of Multimodal Biomarkers for Central Nervous System Disorders4 Opportunities for Precision Medicine5 Standardization and Methodology for Multimodal Biomarkers6 Regulatory Decision Making7 Exploring Opportunities to Move ForwardAppendix A: ReferencesAppendix B: Agenda

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