Nitric Oxide and the Regulation of the Peripheral Circulation

Nitric oxide is involved in the regulation of the circulation in physiologic and pathophysiological conditions. Evidence indicates that alterations in endothelial production of nitric oxide may be involved in the pathogenesis of central hypertension, pulmonary hypertension and renal disease.

Nitric Oxide in the Regulation of Blood Flow: A Historical Overview.- 1. Nitric Oxide in the Regulation of Blood Flow: A Historical Overview.- I: Selected Mechanisms Of Action.- 2. Regulation of Intracellular Ca2+ by Cyclic GMP-Dependent Protein Kinase in Vascular Smooth Muscle Cells.- 3. Oxidants and Vascular Nitric Oxide Signaling.- 4. Role of Na+-K+-ATPase in Nitric Oxide-Induced Relaxation.- 5. Purinergic Receptors, Nitric Oxide, and Regional Blood Flow.- 6. Nitric Oxide Derived from Perivascular Nerves and Endothelium.- 7. Nitric Oxide and Hypertension.- II: Vascular Bed.- A. Cerebral.- 8. Nitric Oxide in Control of the Cerebral Circulation.- B. Pulmonary.- 9. Intravenous Anesthetics in the Pulmonary Circulation.- 10. Inhaled Nitric Oxide Therapy for Acute Respiratory Failure.- 11. Clinical Applications of Inhaled Nitric Oxide.- 12. Nitric Oxide and the Perinatal Pulmonary Circulation.- C. Skeletal.- 13. Nitric Oxide and the Pulmonary Circulation in the Adult.- 14. Role of Nitric Oxide in the Skeletal Muscle Vascular Bed.- D. GI/GU.- 15. Nitric Oxide and the Hepatic Circulation.- 16. Nitric Oxide and the Gastrointestinal Circulation.- 17. Uterine Effects of Nitric Oxide.- 18. NO Effect on Penile Blood Flow and Lower Genitourinary Tract Function.- 19. Role of Nitric Oxide in the Regulation of Renal Blood Flow.- E. Renal.- 20. Role of Nitric Oxide in the Regulation of Renal Function in Conscious Animals.- 21. Modulation of Renal Micro vascular Responsiveness by Nitric Oxide.