Nitric Oxide, Cell Signaling, and Gene Expression
Book Details
Format
Hardback or Cased Book
Book Series
Oxidative Stress and Disease
ISBN-10
0824729609
ISBN-13
9780824729608
Publisher
Taylor & Francis Inc
Imprint
CRC Press Inc
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Nov 1st, 2005
Print length
452 Pages
Weight
725 grams
Product Classification:
Genetics (non-medical)Cellular biology (cytology)
Ksh 54,900.00
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Since the nineteenth century, when engineers were using nitroglycerin to blow up rockbeds, and doctors were prescribing it to relieve angina, scientists have been exploring the incredible and often baffling behavior of nitric oxide. This title showcases the useful diversity of cellular effects elicited by nitric oxide.
Since the nineteenth century, when engineers were using nitroglycerin to blow up rockbeds, and doctors were prescribing it to relieve angina, scientists have been exploring the incredible and often baffling behavior of nitric oxide. In the 1980s, researchers discovered that nitric oxide had the capacity to regulate vascular tone through cyclic GMP, firmly establishing its role as a physiological mediator. Over the last ten years, still further roles have been discovered that relate to nitric oxides unique ability to interact with and modify a wide variety of other molecules and regulators including glutathione, as well as macromolecules such as DNA and proteins. Nitric oxide-driven cell signaling mediated by cGMP, GTPases, and S-nitrosylation Nitric oxides role in hypoxia, gene expression, post-transcriptional control of gene expression, gene regulation in pulmonary pathophysiology, and tumor biology The intriguing concept of mitochondrial nitric oxide synthase as a regulator of mitochondrial bioenergetics and free radical production Modulation of cell metabolism offers cell and molecular biologists, pharmacologists, biochemists, and biomedical researchers, as well as advanced graduate students, the insight and information they need to understand recent developments in this highly fertile area of research.
Nitric Oxide, Cell Signaling, and Gene Expression is the first comprehensive work to showcase the highly useful diversity of cellular effects elicited by nitric oxide. A collection of expert contributors provides cutting-edge information on a variety of topics with tremendous implications in the fields of biology and medicine. These include
Nitric Oxide, Cell Signaling, and Gene Expression
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