Novartis Foundation Symposium 286 – Fatty Acids and Lipotoxicity in Obesity and Diabetes
Book Details
Format
Hardback or Cased Book
Book Series
Novartis Foundation Symposia
ISBN-10
0470057645
ISBN-13
9780470057643
Publisher
John Wiley & Sons Inc
Imprint
John Wiley & Sons Inc
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Nov 23rd, 2007
Print length
222 Pages
Weight
476 grams
Dimensions
23.60 x 16.10 x 1.70 cms
Product Classification:
Clinical & internal medicineClinical and internal medicineBiology, life sciences
Ksh 29,850.00
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Fatty Acid and Lipotoxicity in Obesity and Diabetes deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics include lipid metabolism and adipose tissue biology, and beta-cell function and insulin resistance. Chapters deal with the molecular genetics and molecular physiology of energy homeostasis.
The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic ß cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics include lipid metabolism and adipose tissue biology, and ß cell function and insulin resistance. Chapters deal with the molecular genetics and molecular physiology of energy homeostasis.
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