Novel Enzyme / DNA Inorganic Materials : A New Generation of Biomaterials
Book Details
Format
Paperback / Softback
ISBN-10
1604561912
ISBN-13
9781604561913
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
May 1st, 2008
Print length
130 Pages
Weight
246 grams
Dimensions
22.80 x 15.30 x 0.90 cms
Product Classification:
Genetics (non-medical)
Ksh 9,200.00
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The very first examples of protein/DNA/inorganic nanocomposite materials are described. Surprisingly, the presence of DNA enhanced the properties of the bound protein. The layered inorganic solid, alpha-Zr(IV) phosphate (alpha-Zr(HPO4)2.H2O, abbreviated as alpha-ZrP) served as an excellent host for these studies, and the binding has been carried out under benign conditions (aqueous solutions at room temperature and neutral pH). These novel nanobiocomposite materials provide a simple method for the binding of DNA to negatively charged solids, and such approaches aid in engineering more effective synthetic materials for gene-delivery, RNA-delivery and drug delivery applications.
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